Aloe Vera and Diabetes

Aloe Vera is a succulent, evergreen, perennial plant that grows wild in tropical climes. Can it be useful for diabetics – help in the controlling of high blood sugar and decrease time taken for wound healing among other aspects?

There are a number of studies that believe aloe vera can indeed help with lowering blood sugar diabetic patients. Please know, a number of these studies are on non-human models. Please read the references and speak with your doctor before changing your lifestyle or altering your medication, routine or diet.

Going by the findings, it appears that aloe vera, and in some cases, in combination with other plant extracts, can help diabetic patients in the following ways.

  • Reduction / maintenance of blood glucose​1–8​
  • Improved healing of wounds​9​
  • Protection to the liver​10​

In light of the above, would you consider consuming aloe vera as a part of your daily diet? Do share your thoughts in the comments.

References

  1. 1.
    Okyar A, Can A, Akev N, Baktir G, Sütlüpinar N. Effect of Aloe vera leaves on blood glucose level in type I and type II diabetic rat models. Phytother Res. 2001;15(2):157-161. https://www.ncbi.nlm.nih.gov/pubmed/11268118.
  2. 2.
    Rajasekaran S, Sivagnanam K, Ravi K, Subramanian S. Hypoglycemic effect of Aloe vera gel on streptozotocin-induced diabetes in experimental rats. J Med Food. 2004;7(1):61-66. https://www.ncbi.nlm.nih.gov/pubmed/15117555.
  3. 3.
    Parihar M, Chaudhary M, Shetty R, Hemnani T. Susceptibility of hippocampus and cerebral cortex to oxidative damage in streptozotocin treated mice: prevention by extracts of Withania somnifera and Aloe vera. J Clin Neurosci. 2004;11(4):397-402. https://www.ncbi.nlm.nih.gov/pubmed/15080956.
  4. 4.
    Rajasekaran S, Sivagnanam K, Subramanian S. Antioxidant effect of Aloe vera gel extract in streptozotocin-induced diabetes in rats. Pharmacol Rep. 2005;57(1):90-96. https://www.ncbi.nlm.nih.gov/pubmed/15849382.
  5. 5.
    Rajasekaran S, Sivagnanam K, Subramanian S. Mineral contents of aloe vera leaf gel and their role on streptozotocin-induced diabetic rats. Biol Trace Elem Res. 2005;108(1-3):185-195. https://www.ncbi.nlm.nih.gov/pubmed/16327071.
  6. 6.
    Rajasekaran S, Ravi K, Sivagnanam K, Subramanian S. Beneficial effects of aloe vera leaf gel extract on lipid profile status in rats with streptozotocin diabetes. Clin Exp Pharmacol Physiol. 2006;33(3):232-237. https://www.ncbi.nlm.nih.gov/pubmed/16487267.
  7. 7.
    Pérez Y, Jiménez-Ferrer E, Zamilpa A, et al. Effect of a polyphenol-rich extract from Aloe vera gel on experimentally induced insulin resistance in mice. Am J Chin Med. 2007;35(6):1037-1046. https://www.ncbi.nlm.nih.gov/pubmed/18186589.
  8. 8.
    Román-Ramos R, Flores-Sáenz J, Partida-Hernández G, Lara-Lemus A, Alarcón-Aguilar F. Experimental study of the hypoglycemic effect of some antidiabetic plants. Arch Invest Med (Mex). 1991;22(1):87-93. https://www.ncbi.nlm.nih.gov/pubmed/1819981.
  9. 9.
    Abdullah K, Abdullah A, Johnson M, et al. Effects of Aloe vera on gap junctional intercellular communication and proliferation of human diabetic and nondiabetic skin fibroblasts. J Altern Complement Med. 2003;9(5):711-718. https://www.ncbi.nlm.nih.gov/pubmed/14629848.
  10. 10.
    Can A, Akev N, Ozsoy N, et al. Effect of Aloe vera leaf gel and pulp extracts on the liver in type-II diabetic rat models. Biol Pharm Bull. 2004;27(5):694-698. https://www.ncbi.nlm.nih.gov/pubmed/15133247.

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